Handling the limit of detection by extrapolation

N.T. Longford

Abstract

A general method of estimation with a variable observed subject to a limit of detection is introduced. It is based on extrapolation of the estimates obtained by increasing the limit of detection. The method is supported by theoretical arguments in some special cases, and explored by simulations. Several examples are presented and adaptations for other kinds of censoring explored.

Submitted.
May 2011