Statistical matching as an unconstrained optimisation problem
N. T. Longford

Abstract

Within the potential outcomes framework (Rubin's causal model), balancing the treatment groups, by purposeful subsetting or weighting, is a key step in estimation of the average treatment effect in an observational study. Established methods involve an extensive search of propensity models and distance-based matching. Their results cannot be straightforwardly related to the best balance that might be achieved. Methods for optimal matching or weighting solve nonlinear programming problems by iterative algorithms. We present an algorithm for optimal weighting of one treatment group against a target (standard) or template, which involves no iterations. A recursive formula is applied to avoid numerical inversion of large matrices. The method is applied to studies in neonatal research, concerned with clinical care for preterm born babies in the first few weeks of their lives.

Submitted.

July 2021.